[{"_1":2,"_131":-5,"_132":-5},"loaderData",{"_3":4,"_9":10},"root",{"_5":6,"_7":8},"locale","id","isCms",false,"routes/tags/$slug",{"_11":12,"_13":14,"_48":49,"_118":119,"_125":121,"_129":124,"_130":-5},"slug","kanker-otak","ads",[15,40],{"_6":16,"_17":18,"_19":20,"_21":22,"_23":24,"_25":24,"_26":27,"_28":29,"_27":30,"_31":32,"_33":34,"_35":36,"_37":-5,"_38":39},"019cc7ba-cc99-73c7-8531-f093038fe91a","position_id","2f16d5c6-a732-4e00-b8c6-6306c0d32904","position_name","Sidebar Middle","position_code","sidebar_middle","name","Ramadan Mubarak 3","code","type","image","link","www.indonesiawindow.com","banners/PUGYsfPWy2qGTP9P9LOiwwUlZtOJACN5Tf1xowFn.png","is_active",true,"description","","image_url","https://indonesiawindow.sgp1.cdn.digitaloceanspaces.com/banners/PUGYsfPWy2qGTP9P9LOiwwUlZtOJACN5Tf1xowFn.png","visitor","created_at","2026-03-07",{"_6":41,"_17":42,"_19":43,"_21":44,"_23":45,"_25":45,"_26":27,"_28":29,"_27":46,"_31":32,"_33":34,"_35":47,"_37":-5,"_38":39},"019cc7b2-e7e4-703f-adb8-56638bb111c2","136cc14b-de52-4760-b610-f65531f31a3f","Tag Top","tag_top","Ramadan Kareem 1","banners/pCDDkaqLKdunP3khU4OKAXxHW9HLl9M227FCehXR.png","https://indonesiawindow.sgp1.cdn.digitaloceanspaces.com/banners/pCDDkaqLKdunP3khU4OKAXxHW9HLl9M227FCehXR.png","posts",[50],{"_6":51,"_52":53,"_11":54,"_55":56,"_57":58,"_59":60,"_61":62,"_63":64,"_65":66,"_67":68,"_69":70,"_71":72,"_73":74,"_75":76,"_77":78,"_79":78,"_80":81,"_27":82,"_83":34,"_84":85,"_35":86,"_87":88,"_89":90,"_115":116,"_38":117},"019c2400-a28c-70c3-80f0-46b1416ef8ed","title","Vaksin personalisasi pertama di dunia untuk kanker otak anak yang mematikan dalam tahap uji klinis","vaksin-personalisasi-pertama-di-dunia-untuk-kanker-otak-anak-yang-mematikan-dalam-tahap-uji-klinis","main_id","019bb73f-297b-7103-96b7-87ea173dc182","main_name","Iptek","main_slug","iptek-id","date","2026-02-03 00:00:00","author_id","019bb745-b426-73a2-9a49-5ddcb6765ea0","author_name","indowin","full_name","Indonesia Window","author_firstname","Indonesia","author_slug","indonesiawindow","content","

Vaksin kanker mRNA yang dipersonalisasi telah menunjukkan hasil menjanjikan pada orang dewasa penderita kanker langka yang sulit diobati, termasuk kanker pankreas dan melanoma.

Sydney, Australia (Xinhua/Indonesia Window) – Australia meluncurkan uji klinis pertama di dunia yang menggunakan vaksin mRNA yang dipersonalisasi untuk mengobati anak-anak dan remaja pengidap tumor otak stadium lanjut atau yang resisten terhadap pengobatan.

Studi PaedNEO-VAX, yang dipimpin bersama oleh Universitas Queensland (UQ) Australia dan Institut Penelitian Kesehatan dan Medis Australia Selatan (South Australian Health and Medical Research Institute/SAHMRI), akan melibatkan sejumlah pasien di delapan rumah sakit anak di seluruh Australia, menawarkan harapan baru bagi keluarga yang menghadapi penyakit masa kanak-kanak paling mematikan di negara tersebut, menurut pernyataan UQ pada Selasa (3/2).

Pimpinan klinis dari SAHMRI, Jordan Hansford, mengatakan uji klinis tersebut tersedia bagi pasien anak dengan tumor otak tingkat tinggi yang mengalami kekambuhan dan tidak responsif, termasuk glioma dan medulloblastoma.

Fase I akan menilai keamanan, diikuti oleh Fase II untuk menguji efektivitas serta dampaknya terhadap kelangsungan hidup dan kualitas hidup, tutur Hansford.

Brandon Wainwright, pimpinan ilmiah untuk uji klinis tersebut dari Institut Frazer di UQ, mengatakan bahwa vaksin kanker mRNA yang dipersonalisasi telah menunjukkan hasil menjanjikan pada orang dewasa penderita kanker langka yang sulit diobati, termasuk kanker pankreas dan melanoma.

\"Setelah mengidentifikasi beberapa penanda kanker unik pada tumor setiap anak menggunakan pengurutan genom dan analisis data tingkat lanjut, kami akan memilih target-target vaksin spesifik tumor,\" kata Wainwright.

Vaksin-vaksin yang disesuaikan untuk setiap anak akan diproduksi di Negara Bagian Queensland, Australia, oleh Southern RNA dan dikirim ke lokasi uji klinis untuk pemberian dosis dalam waktu sekitar 10 pekan setelah perekrutan uji klinis, yang didukung oleh pendanaan federal sebesar 2,58 juta dolar Australia atau sekitar 1,81 juta dolar AS, papar para peneliti.

*1 dolar Australia = 11.66 rupiah

**1 dolar AS = 16.800 rupiah

Laporan: Redaksi

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