[{"_1":2,"_116":-5,"_117":-5},"loaderData",{"_3":4,"_9":10},"root",{"_5":6,"_7":8},"locale","id","isCms",false,"routes/tags/$slug",{"_11":12,"_13":14,"_15":16,"_103":104,"_110":106,"_114":109,"_115":-5},"slug","sel-natural-killer","ads",[],"posts",[17],{"_6":18,"_19":20,"_11":21,"_22":23,"_24":25,"_26":27,"_28":29,"_30":31,"_32":33,"_34":35,"_36":37,"_38":39,"_40":41,"_42":43,"_44":20,"_45":46,"_47":48,"_49":50,"_51":20,"_52":53,"_54":55,"_56":57,"_58":59,"_100":101,"_68":102},"019bb766-9f03-733e-9432-cb01cc8bdb4c","title","COVID-19 – Kementerian teliti fukoidan kandungan alga untuk tingkatkan imun","covid-19-kementerian-teliti-fukoidan-kandungan-alga-untuk-tingkatkan-imun","main_id","019bb73f-297b-7103-96b7-87ea173dc182","main_name","Iptek","main_slug","iptek-id","date","2021-10-03 13:59:25","author_id","019bb745-b426-73a2-9a49-5ddcb6765ea0","author_name","indowin","full_name","Indonesia Window","author_firstname","Indonesia","author_slug","indonesiawindow","content","Bekasi, Jawa Barat (Indonesia Window) – Kementerian Kelautan dan Perikanan (KKP) tengah melakukan penelitian tentang manfaat fukoidan kandungan alga guna meningkatkan imun melawan COVID-19, menurut laman resmi kementerian yang dikutip pada Ahad.

KKP melalui Badan Riset dan Sumber Daya Manusia (BRSDM) telah melakukan berbagai riset di sektor kelautan dan perikanan, termasuk untuk kesehatan.

Plt. Kepala BRSDM Kusdiantoro menambahkan, riset fukoidan dilaksanakan oleh Loka Riset Mekanisasi Pengolahan Hasil Perikanan (LRMPHP), di bawah pengawasan Pusat Riset Perikanan BRSDM.

Fukoidan merupakan polisakarida yang sebagian besar tersusun oleh rantai fukosa dan gugus sulfat, sehingga sering disebut juga sebagai polisakarida sulfat. Polisakarida adalah salah satu penyusun dinding sel pada alga coklat yang cukup melimpah di Indonesia.

Peneliti LRMPHP Iwan Malhani Al Wazzan mengatakan, fukoidan diperoleh dengan mengekstrak alga Sargassum sp. yang sejauh ini baru dimanfaatkan sebagai pakan ternak dan pupuk.

“Hasil studi menyatakan, fukoidan Sargassum sp. memiliki beberapa aktivitas biologis, salah satunya adalah sebagai immunomodulator. Fukoidan Sargassum sp. mampu meningkatkan respon imun dengan cara mengaktivasi neutrofil, sel NK, meng-upregulate produksi sitokin pro-inflamasi IL-6, IL-8, dan TNF-α serta menunda apoptosis spontan pada sel-sel tersebut,” terangnya.

Secara umum, fukoidan mempercepat proses penyingkiran patogen dengan mengaktivasi sel natural killer atau NK, menstimulasi faktor-faktor antiviral inang, dan membantu produksi sel dendritik.

“Fukoidan juga mampu menunda apoptosis spontan pada sel-sel pertahanan tubuh sehingga mampu memperpanjang umur sel-sel tersebut. Tubuh selalu dalam keadaan siap ketika terjadi infeksi. Seperti inilah mekanisme immunomodulator yang dilakukan oleh fukoidan,” jelas Iwan.

Kemampuan fukoidan untuk mediasi sel yang kuat dan kemampuan meningkatkan respons imun yang baik sebenarnya merupakan potensi yang sangat menjanjikan untuk digunakan sebagai adjuvan dalam pengembangan vaksin, lanjutnya.

Adjuvan merupakan sebuah substansi bioaktif, yang membantu meningkatkan respons imun bersamaan dengan antigen yang terkandung dalam vaksin.

Laporan: Redaksi","excerpt","Bekasi, Jawa Barat (Indonesia Window) – Kementerian Kelautan dan Perikanan (KKP) tengah melakukan penelitian tentang manfaat fukoidan kandungan alga guna mening...","seo_kw","seo_title","","seo_description","fukoidan mempercepat proses penyingkiran patogen dengan mengaktivasi sel natural killer atau NK, menstimulasi faktor-faktor antiviral inang, dan membantu produksi sel dendritik.","image","2021/10/the-tampa-bay-estuary-program-btsAoomBCeM-unsplash-scaled.jpg","image_alt","image_caption","Ilustrasi. (The Tampa Bay Estuary Program on Unsplash)","image_url","https://indonesiawindow.sgp1.cdn.digitaloceanspaces.com/2021/10/the-tampa-bay-estuary-program-btsAoomBCeM-unsplash-scaled.jpg","status","publish","tags",[60,76,83,89,94],{"_6":61,"_62":63,"_64":65,"_11":66,"_49":-5,"_67":-5,"_68":69,"_70":69,"_71":72},"019bb744-4a0b-724d-831d-0565ec26d7b4","old_id",6441,"name","imunitas terhadap covid-19","imunitas-terhadap-covid-19","description","created_at","2026-01-13T12:11:04.000000Z","updated_at","pivot",{"_73":18,"_74":61,"_68":75,"_70":75},"post_id","tag_id","2026-01-13T12:48:34.000000Z",{"_6":77,"_62":78,"_64":79,"_11":80,"_49":-5,"_67":-5,"_68":81,"_70":81,"_71":82},"019bb744-744c-703a-bdbf-0cbfbdf5b9cd",10867,"manfaat alga","manfaat-alga","2026-01-13T12:11:15.000000Z",{"_73":18,"_74":77,"_68":75,"_70":75},{"_6":84,"_62":85,"_64":86,"_11":87,"_49":-5,"_67":-5,"_68":81,"_70":81,"_71":88},"019bb744-7450-73ed-8cf9-e74132711cc0",10869,"fukoidan alga","fukoidan-alga",{"_73":18,"_74":84,"_68":75,"_70":75},{"_6":90,"_62":91,"_64":92,"_11":12,"_49":-5,"_67":-5,"_68":81,"_70":81,"_71":93},"019bb744-7452-720e-bed1-46f48a1764ce",10871,"sel natural killer",{"_73":18,"_74":90,"_68":75,"_70":75},{"_6":95,"_62":96,"_64":97,"_11":98,"_49":-5,"_67":-5,"_68":81,"_70":81,"_71":99},"019bb744-7457-702f-a586-e8bfa51ed6e5",10873,"Sargassum sp.","sargassum-sp",{"_73":18,"_74":95,"_68":75,"_70":75},"comments",[],"2021-10-03","pagination",{"_105":106,"_107":106,"_108":109,"_110":106,"_111":106,"_112":113},"count",1,"total","perPage",12,"currentPage","totalPages","links",{},"pageSize","error","actionData","errors"]